重组小鼠MIP-1γ/CCL9/CCL10

产品货号：

GS4605

中文名称：

重组小鼠MIP-1γ/CCL9/CCL10

英文名称：

Recombinant Murine Macrophage Inflammatory Protein-1 gamma/CCL9/CCL10

产品规格：

5μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 11.6kDa,a single non-glycosylated polypeptide chain containing 101 amino acids.
储存条件：冷冻（-20℃）

概述

Murine CCL9/10 is belonging to the CC chemokine family.It is encoded by the gene CCL9.MRP-2(CCL9/10)was isolated from a murine macrophage cell line,RAW 264.7.MRP-2 shows a 51%sequence identity at the protein level to MRP-1(C10)and 46%identity to MIP-1-alpha(CCL3).The functional receptor for CCL9/10 has been identified as CCR1.In contrast,other CCR1 ligands,CCL3/MIP-1alpha and CCL5/RANTES are considered to be primary CCR1 ligands in inflammatory responses.CCL9 can activate osteoclasts suggesting an important role for it in bone resorption.Murine CCL9/10 is 75%amino acid identical to rat CCL9/10.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 0.1-10ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rMuMIP-1γ/CCL9/CCL10 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

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